Thiopurine Drug Response (TPMT)

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Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers

Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers

Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers

Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers

Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers

Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers

Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers

Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers

Overview

The thiopurine drugs – azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) – are commonly used to treat blood cancers, autoimmune conditions, inflammatory bowel disease, and solid organ transplant rejections. Some individuals are more sensitive to this drug and at high risk of toxicity.   Genetic testing can aid in identifying people with a high risk of toxicity who may require a lower than normal dose. Follow the Read More button above to learn more.

Currently, this type of genetic testing is not readily available in Canada.  Discuss this test with your physician to see if it could be beneficial for you.

Public Providers

Private Providers